United States securities and exchange commission logo

                        August 11, 2023

       Mei Mei Hu
       Chief Executive Officer
       Vaxxinity, Inc.
       505 Odyssey Way
       Merritt Island, Florida 32953

                                                        Re: Vaxxinity, Inc.
Statement on Form S-3
                                                            Filed August 9,
                                                            File No. 333-273822

       Dear Mei Mei Hu:

              This is to advise you that we have not reviewed and will not
review your registration

               Please refer to Rules 460 and 461 regarding requests for
acceleration. We remind you
       that the company and its management are responsible for the accuracy and
adequacy of their
       disclosures, notwithstanding any review, comments, action or absence of
action by the staff.

                                                        Please contact Jimmy
McNamara at 202-551-7349 with any questions.


                        Division of Corporation Finance

                        Office of Life Sciences
       cc:                                              Yasin Keshvargar